Scientists are always on the prowl for a cure-all. A compound that solves all of our medical issues and not produces any side effects. We are also searching for an elixir that prevents the time-bound process of aging. Resveratrol may provide us with a few solutions to some of our problems. Although it is not a cure-all, it does possess powerful qualities that benefit human health.
Resveratrol is polyphenols with numerous bioactive effects. Polyphenols are naturally occurring organic compounds, plant-based micronutrients. Resveratrol is present in the skin and seed or red grapes, which means that they are effectively present in red wine. It is also present in berries, peanuts, plums, and apples. However, the concentration of resveratrol is low in these food sources. So, how does one boost their resveratrol intake? From high concentration, resveratrol supplements available in the market. The resveratrol present in these supplements is from the roots of an Asian plant known as Polygonum cuspidatum. Others may derive resveratrol from red grape extracts as well.
BENEFITS AND BIOACTIVE EFFECTS OF RESVERATROL
Resveratrol is a potent antioxidant and is popular because of this property. The foundation of resveratrol function is its ability to reduce and prevent inflammatory processes (a common reason for disease manifestation and progression). Free radicals are the body’s natural byproduct of metabolism. But these free radicals are unstable and possess the ability to wreak havoc in a short time (oxidative damage). Free radicals can attack DNA, resulting in genetic mutations and increased susceptibility to cancer. Antioxidants neutralize these free radicals,
thereby preventing excess damage within the body.
Resveratrol can prevent the formation and spread of cancer cells.
It changes the gene expression of cancer cells; inhibits their growth by stopping replication and progression. By interfering with the hormonal expression of cancer cells, it particularly prevents the spread of hormone dependant cancers (breast, prostate, uterine, etc.).
Phytoestrogens are plant-derived nonsteroidal compounds. They are functionally and structurally similar to estrogen, and resveratrol is one of them. The transresveratrol binds to estrogen receptors and promotes estrogenic activity. As a result, resveratrol supplements can alleviate menopausal symptoms. Regular intake can relieve postmenopausal women of their symptoms such as hot flashes and night sweats. Researches show that topically applying resveratrol will decelerate the aging skin and provide support to estrogen-deprived skin.
Another crucial benefit is that resveratrol promotes bone health in women going through menopause. Regular supplementation will prevent bone loss and increase bone mineral density.
As a result, there is a decrease in the risk of developing osteoporosis after menopause.
An overlooked menopausal symptom is a decline in mood and cognition. Research shows that frequent and consistent intake of resveratrol supplements improves mood and cognition in postmenopausal women.
● Maintains cholesterol levels: it increases the levels of good cholesterol (HDL) and lowers bad cholesterol (LDL), therefore, preventing the build-up of cholesterol in blood vessels and organs.
● Lowers blood pressure: increases the production of nitric oxide, a substance that relaxes the blood vessels.
● It will prevent fat deposition within the blood vessels (atherosclerosis), the main antagonist of stroke and heart attacks. Resveratrol acts specifically during the early stages and prevents the hardening of the blood vessels with fatty deposits.
● Assist in the recovery of the heart muscles after a heart attack.
Perhaps the most sought-after benefit of resveratrol is its anti-aging property. Resveratrol increases the expression of the SIRT1 gene, which activates the enzyme sirtuin. The increase in the activity of sirtuin increases the production and action of the SIRT1 protein. This protein is an anti-aging protein, and it also promotes DNA repair.
In Alzheimer’s disease, plaques and protein tangles are deposited irregularly within several areas of the brain. The imbalance between oxidative damage and antioxidant defenses contributes to the pathology and progression of Alzheimer’s disease. Resveratrol will protect the nerves from oxidative damage. Also, it will prevent the build-up of plaque and protein tangles in the brain. Resveratrol also protects against other neurodegenerative diseases such as
Huntington’s disease, ALS, and Parkinson’s. Another research reveals that resveratrol can prevent secondary damage after a brain injury, stroke, or brain hemorrhage.
There are countless benefits of resveratrol supplements. This plant-derived compound has come a long way and yet has a long way to go. Numerous research supports the favorable properties of resveratrol. This plant-derived compound in making a positive impact on our health. And one day, we will uncover its exceptional merit.